CC112 inhibited the mycelial growth of several plant pathogens, including , causing damping-off on ginseng. The control efficacies of CC112 against by seed dipping in LB and BSM broth diluted 10 times, soil dipping, and soil drenching with LB broth diluted 10 times were 65.8%, 67.1%, and 64.2%, respectively. Treatment of soil drenching with the 100 times diluted prototype of CC112 against and Pythium sp. by soil revealed control efficacies of 77.3% and 65.7%, respectively. These results indicate that CC112 is a prospective biofungicide for the biological control of ginseng damping off.